Glipizide high purity antidiabetics
Chinese name: glipizide
1- cyclohexyl-3 -{4-[2-(5-methylpyrazine-2-amide) -ethyl]
benzenesulfonyl} urea
English name: Glipizide
Chemical formula: C21H27N5O4S
Molecular weight: 445.54
CAS no. : 29094-61-9
EINECS no. : 249-427-6
Glipizide is the second generation of sulfonylureas hypoglycemic
drugs, and has lipid-lowering and anticoagulant effects. Its
hypoglycemic effect is rapid and strong, about 1000 times that of
toluensulfonylurea, the efficacy is similar to glibenzorea, the
mechanism of action is to stimulate the β cells of the islet,
promote the increase of insulin secretion, and also stimulate the α
cells of the islet to inhibit the secretion of hyperglycemia. Its
mode of action is similar to that of chlorpropirea with lower
toxicity and no teratogenicity. In addition, it is believed that
glipizide can inhibit the decomposition of liver glycogen, promote
muscle use and consumption of glucose; It is also possible to
enhance insulin action by changing the insulin response of target
tissues through extrapancreas, so some patients can effectively
control blood glucose for 24 hours with a single dose. Otherwise
literature reports, glipizide can correct early diabetes tiny blood
circulation obstacle, reduce plasma levels of three acyl glycerin,
speed up the transformation of cholesterol to HDL, can also reduce
platelet cohesion and improve the fibrous protein decomposition,
absorption capacity, which can resist platelet aggregation, and
slow capillary endothelial injury and thrombosis and It may have
prophylactic effect on microvascular diseases. Using controlled
release technology, the drug is released slowly, so as to achieve
lasting hypoglycemic effect, the efficacy can be maintained for
24h, can reduce fasting blood glucose and postprandial blood
glucose.
Our Competitive Advantages:
1. Rich experience: we specialize in this field for many years, our
steroids have been exported almost over the world. Such as USA,
Canada, UK, Brazil, Germany, Russia, Australia, Greece, Poland,
Bulgaria, Rumania, Netherlands, Sweden, Ukraine, Latvia, Lithuania,
Ireland, Austria, Iran, Turkey, Mexico, Thailand, India, Malaysia,
Singapore, other Middle East countries, European countries,
American countries and more Areas.
2. Great quality: High purity and Favorable price. Good quality is
the first base of our success. All of our products enjoys high
purity. Thus, it can make sure your demand. Welcome order the
samples, MOQ just 10 grams.
3. Safe and fast delivery: Lots of different discreet safe packing
methods, experience in choosing express, 4~7 days to arrive,
successful rate 99%.
4. Experiential order and cooperation: Besides raw powders, we
offer hormone solution and Recipes. We can teach you or discuss how
to make hormone solution on the site. Any discussion and question
is welcome!
Packaging & Service:
1. Mass stock, to make sure delivery promptly every day when the
payment is done.
2. Having been engaged in this field for years, we have
sophisticated and professional logistics department, which can
guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional
enough to provide you a safe package. It also avoid a lot of
emergency happen during the delivery so that high customs pass is
guaranteed. Unique ways to ship 10grams to 20 kilograms powders(or
100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking number are provided within 24 hours
as soon as receiving the payment. Updated tracking code will be
provided every other day just for you can hold a palm of your
package.
5. Perfect after-sale service: Any questions or problems happened
after receiving the product.
Please feel free to contact us. 24/7 online to solve your various
problems!
